ZSM-5/cordierite monolith catalyst was synthesized by an in-situ hydrothermal method. The effects of amount of tetrapropyl ammonium hydroxide (TPAOH), n(H₂O)/n(SiO₂) ratio and crystallization temperature on the deposition of ZSM-5 on cordierite supporter were investigated. The results reveal that the deposition of ZSM-5 on the cordierite supporter is related to the amount of TPAOH. When n(TPAOH)/n(SiO₂)≤0.2, a desired deposition of ZSM-5 zeolite can be obtained via the adjustment of temperature or n(H₂O)/n(SiO₂) ratio. When n(TPAOH)/n(SiO₂)＞0.2, a high alkalinity leads to the dissolution of the precursor sol, making that zeolite tends to grow in solution rather than on the cordierite surface, and thus decrease the deposition of zeolite on the cordierite. When n(TPAOH)/n(SiO₂≤0.2, the deposition of ZSM-5 increases with the decrease of n(H₂O)/n(SiO₂) ratio, and the maximum deposition amount is 42.8%. The crystal particle size and the loading amount decrease with the decrease of the crystallization temperature. According to the catalytic activity of monolith catalysts for NO, a high loading amount and a small crystal particle size of ZSM-5 zeolite on the surface of the monolith catalyst lead to a high specific surface area, which can favor the NO catalytic oxidation.