The hierarchical pore SAPO-11 molecular sieves were synthesized by a conventional one-step hydrothermally method with acid-base treatment sisal fibers. The morphology, pore structure properties and acid types of the hierarchical pore SAPO-11 molecular sieves were investigated. The catalytic hydroisomerization performance of hierarchical pore SAPO-11 catalysts with 0.5%Pt loading was evaluated with n-dodecane as a material. The results indicate that the sample synthesized by adding sisal fiber treated with acid and alkali has a greater specific surface area and a mesoporous structure, and increases a ratio of B acid to L acid in the SAPO-11 molecular sieve pore. The SAPO-11 catalyst sample exhibits the excellent catalytic performance in the n-dodecane hydroisomerization. The n-dodecane conversion rate is 95.36%, and the isomer yield is 69.36% at the reaction temperature of 320 oC, reaction space velocity of 2.0 h?1, reaction pressure of 2 MPa, and hydrogen and oil volume ratio of 200:1.